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  • Katrin Quigley
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在 10月 20, 2025 由 Katrin Quigley@katrinquigley
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The new England Journal Of Medicine


Hypoxemia (additionally spelled hypoxaemia) is an abnormally low level of oxygen in the blood. More specifically, it's oxygen deficiency in arterial blood. Hypoxemia is normally brought on by pulmonary illness. Sometimes the concentration of oxygen in the air is decreased leading to hypoxemia. Hypoxemia refers to the low stage of oxygen in arterial blood. Tissue hypoxia refers to low ranges of oxygen within the tissues of the physique and BloodVitals the time period hypoxia is a common term for low ranges of oxygen. Hypoxemia is normally brought on by pulmonary disease whereas tissue oxygenation requires additionally sufficient circulation of blood and perfusion of tissue to satisfy metabolic calls for. Hypoxemia is usually outlined by way of reduced partial stress of oxygen (mm Hg) in arterial blood, but also by way of decreased content of oxygen (ml oxygen per dl blood) or share saturation of hemoglobin (the oxygen-binding protein inside crimson blood cells) with oxygen, which is both found singly or together.


This definition would include oxygen carried by hemoglobin. The oxygen content of blood is thus sometimes viewed as a measure of tissue delivery somewhat than hypoxemia. Just as extreme hypoxia can be referred to as anoxia, excessive hypoxemia will be known as anoxemia. In an acute context, hypoxemia can cause signs corresponding to these in respiratory distress. These include breathlessness, an increased charge of breathing, use of the chest and abdominal muscles to breathe, and lip pursing. Chronic hypoxemia could also be compensated or uncompensated. The compensation could cause symptoms to be overlooked initially, nevertheless, additional disease or a stress resembling any increase in oxygen demand may finally unmask the present hypoxemia. In a compensated state, blood vessels supplying much less-ventilated areas of the lung might selectively contract, BloodVitals SPO2 to redirect the blood to areas of the lungs which are higher ventilated. However, in a chronic context, BloodVitals and if the lungs are usually not well ventilated usually, this mechanism can lead to pulmonary hypertension, overloading the fitting ventricle of the center and causing cor pulmonale and proper sided coronary heart failure.


Polycythemia can also occur. In children, chronic hypoxemia could manifest as delayed progress, neurological growth and motor development and decreased sleep quality with frequent sleep arousals. Other symptoms of hypoxemia may include cyanosis, digital clubbing, blood oxygen monitor and signs which will relate to the cause of the hypoxemia, together with cough and hemoptysis. Serious hypoxemia sometimes occurs when the partial pressure of oxygen in blood is lower than 60 mmHg (8.0 kPa), the start of the steep portion of the oxygen-hemoglobin dissociation curve, where a small lower within the partial stress of oxygen leads to a large lower within the oxygen content material of the blood. Severe hypoxia can result in respiratory failure. Hypoxemia refers to inadequate oxygen within the blood. Thus any cause that influences the speed or quantity of air getting into the lungs (ventilation) or any trigger that influences the transfer of air from the lungs to the blood could cause hypoxemia.


As well as these respiratory causes, BloodVitals cardiovascular causes similar to shunts can also result in hypoxemia. Hypoxemia is attributable to 5 categories of etiologies: hypoventilation, ventilation/perfusion mismatch, BloodVitals right-to-left shunt, diffusion impairment, and low PO2. Low PO2 and hypoventilation are related to a traditional alveolar-arterial gradient (A-a gradient) whereas the other categories are associated with an elevated A-a gradient. If the alveolar ventilation is low, BloodVitals there is not going to be enough oxygen delivered to the alveoli for the body's use. This can cause hypoxemia even when the lungs are normal, as the trigger is in the brainstem's management of ventilation or within the body's inability to breathe successfully. Respiration is controlled by centers within the medulla, which affect the rate of respiratory and the depth of every breath. This is influenced by the blood degree of carbon dioxide, as determined by central and peripheral chemoreceptors situated within the central nervous system and BloodVitals experience carotid and BloodVitals SPO2 aortic bodies, respectively. Strokes, epilepsy and cervical neck fractures can all injury the medullary respiratory centres that generates rhythmic impulses and transmit them alongside the phrenic nerve to the diaphragm, BloodVitals the muscle that's accountable for BloodVitals respiration.

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引用: katrinquigley/7326597#2